Detalhe da pesquisa
1.
Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors.
Proc Natl Acad Sci U S A
; 120(32): e2216532120, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37523561
2.
Genomic heterogeneity and copy number variant burden are associated with poor recurrence-free survival and 11q loss in human papillomavirus-positive squamous cell carcinoma of the oropharynx.
Cancer
; 127(15): 2788-2800, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33819343
3.
Hydroxyurea-stalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair.
Mol Cell
; 37(4): 492-502, 2010 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-20188668
4.
TRAF3/CYLD mutations identify a distinct subset of human papillomavirus-associated head and neck squamous cell carcinoma.
Cancer
; 123(10): 1778-1790, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28295222
5.
Characterization of HPV and host genome interactions in primary head and neck cancers.
Proc Natl Acad Sci U S A
; 111(43): 15544-9, 2014 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25313082
6.
De-Escalated Therapy and Early Treatment of Recurrences in HPV-Associated Head and Neck Cancer: The Potential for Biomarkers to Revolutionize Personalized Therapy.
Viruses
; 16(4)2024 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38675879
7.
Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs.
J Biol Chem
; 292(48): 19607, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29196570
8.
PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination.
EMBO J
; 28(17): 2601-15, 2009 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-19629035
9.
Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis.
J Pathol
; 227(4): 456-69, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22513871
10.
Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints.
Nature
; 444(7119): 633-7, 2006 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-17136093
11.
Tumor suppressor Lzap regulates cell cycle progression, doming, and zebrafish epiboly.
Dev Dyn
; 240(6): 1613-25, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21523853
12.
Direct Comparison of HPV16 Viral Genomic Integration, Copy Loss, and Structural Variants in Oropharyngeal and Uterine Cervical Cancers Reveal Distinct Relationships to E2 Disruption and Somatic Alteration.
Cancers (Basel)
; 14(18)2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36139648
13.
NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer.
Oncotarget
; 13: 707-722, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35634245
14.
Comprehensive Viral Genotyping Reveals Prognostic Viral Phylogenetic Groups in HPV16-Associated Squamous Cell Carcinoma of the Oropharynx.
Mol Cancer Res
; 20(10): 1489-1501, 2022 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35731223
15.
Erratum: Exploring APOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.
iScience
; 25(10): 105271, 2022 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36248736
16.
Exploring ABOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.
iScience
; 25(10): 105077, 2022 Oct 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36164654
17.
Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule.
Front Mol Biosci
; 9: 823195, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35720128
18.
Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound.
Nat Med
; 8(3): 282-8, 2002 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-11875500
19.
Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors.
Nat Med
; 10(12): 1321-8, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15558054
20.
Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.
Clin Cancer Res
; 27(15): 4338-4352, 2021 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33994371